You start at the Fori Imperiali with the Colosseum behind you, pass Piazza Venezia and the Circo Massimo, then run out to the Basilica di San Paolo before following the Tiber toward Castel Sant'Angelo and Via della Conciliazione. The route continues north to Foro Italico and Ponte Milvio, comes back through Piazza del Popolo, Piazza di Spagna and Piazza Navona, and finishes inside the Circo Massimo. Elevation stays between about 8 and 31 metres above sea level. Entry is through the organiser's online registration platform.
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